Newly identified PET biomarker predicts success of immune checkpoint blockade therapy

PET imaging of 124I-αGal-1 predicts ICB therapy. Credit: N Liu and X Yang, et al. Peking University, Beijing, China. The protein galectin-1 (Gal-1) has been identified as a new PET imaging biomarker for immune checkpoint blockade (ICB) therapy, allowing physicians to predict the tumor responses before beginning treatment. Information garnered from Gal-1 PET imaging could…

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Deep learning-based whole-body PSMA PET/CT attenuation correction utilizing Pix-2-Pix GAN

AI-generated PET results shown overlaid on CT. Credit: Oncotarget (2024). DOI: 10.18632/oncotarget.28583 A new research paper was published in Oncotarget, titled “Deep learning-based whole-body PSMA PET/CT attenuation correction utilizing Pix-2-Pix GAN.” Radiation dosage limits the sequential PET/CT studies oncology patients can undergo during their treatment follow-up course. In this new study, researchers from the National…

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Low-cost MRI paired with AI produces high-quality results

First introduced five decades ago, MRI scanners are now a cornerstone of modern medicine, vital for diagnosing strokes, tumors, spinal conditions and more, without exposing patients to radiation. A magnetic resonance imaging device built with off-the-shelf parts and paired with AI matched the performance of high-end MRI machines, according to a study published Thursday that could…

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Study introduces hyperspectral dark-field microscopy for rapid and accurate identification of cancerous tissues

Freshly dissected tissue (lower left) and its pathology-prepared slide with identified tumor regions by a pathologist (upper left), and a pseudo-color image of hyperspectral dark-field microscopy (HSDFM) data cube (middle) region marked on the tissue images on the left. The HSDFM generates an image where each pixel contains a spectral signature corresponding to tissue composition….

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Lung cancer is the deadliest of all cancers, and screening could save many lives—if more people could access it

Credit: CC0 Public Domain Many medical organizations have been recommending lung cancer screening for decades for those at high risk of developing the disease. But in 2022, less than 6% of people in the U.S. eligible for screening actually got screened. Compared with other common cancer screenings, lung cancer screening rates fall terribly behind. For…

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